C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: proprotein convertase subtilisin/kexin type 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000618548 PCSK6-005 ENSG00000140479 9606 - 15:101303934-101489744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000618548
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000618548 0.818±0.00 3.437±0.00 0.247±0.00 7.302±5.93 2.220±0.00 1.061±0.44 6.079±0.00 0.617±0.00 38.175±0.00 2.415±0.00 2.476±2.35 4.752±0.02 13.115±2.25 2.834±0.32

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004175 IDA endopeptidase activity
GO:0004252 IDA:IEA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0005783 IEA endoplasmic reticulum
GO:0005796 TAS Golgi lumen
GO:0006508 IEA proteolysis
GO:0008201 IDA heparin binding
GO:0008233 IEA peptidase activity
GO:0009100 IDA glycoprotein metabolic process
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016485 IDA protein processing
GO:0016486 IDA peptide hormone processing
GO:0030510 TAS regulation of BMP signaling pathway
GO:0031012 IDA extracellular matrix
GO:0032455 TAS nerve growth factor processing
GO:0032902 IDA nerve growth factor production
GO:0032940 IDA secretion by cell
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048406 IDA nerve growth factor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000098391 Pcsk6-002 protein_coding Mus_musculus 0 3507
ENSMUST00000055576 Pcsk6-001 protein_coding Mus_musculus 0 2183
ENSMUST00000176209 Pcsk6-003 protein_coding Mus_musculus 0 1387
ENSMUST00000177369 Pcsk6-005 retained_intron Mus_musculus 0 451

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