C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase-activated protein kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000621469 MAPKAPK3-201 ENSG00000114738 9606 + 3:50617131-50649297 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000621469
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000621469 3.470±0.00 1.123±0.00 7.465±0.00 1.823±0.00 16.049±10.23 1.361±0.00 1.664±0.00 7.737±0.00 18.444±0.00 5.362±2.89 1.630±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0001 VISTA 3:50299047-50902727

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0002224 ISS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004672 IEA protein kinase activity
GO:0004674 IEA:IDA protein serine/threonine kinase activity
GO:0004708 TAS MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006950 TAS response to stress
GO:0007165 TAS signal transduction
GO:0007265 TAS Ras protein signal transduction
GO:0009103 IEA lipopolysaccharide biosynthetic process
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0031965 IDA nuclear membrane
GO:0032496 ISS response to lipopolysaccharide
GO:0034097 IDA response to cytokine
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0044351 ISS macropinocytosis
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0051403 TAS stress-activated MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000035194 Mapkapk3-001 protein_coding Mus_musculus 0 1687
ENSMUST00000155860 Mapkapk3-004 retained_intron Mus_musculus 0 857
ENSMUST00000143487 Mapkapk3-003 retained_intron Mus_musculus 0 640
ENSMUST00000128175 Mapkapk3-008 retained_intron Mus_musculus 0 379
ENSMUST00000016672 Mapkapk2-001 protein_coding Mus_musculus 0 366
ENSMUST00000141674 Mapkapk3-006 processed_transcript Mus_musculus 0 254
ENSMUST00000134682 Mapkapk3-005 protein_coding Mus_musculus 2e-18 99

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