C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcription factor 7-like 2 (T-cell specific, HMG-box)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000004415 tcf7l2 7955 - 12:32666837-32790417 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000005562 tcf7l2-007 32668787-32790288 protein_coding
  ENSDART00000009237 tcf7l2-002 32668787-32790288 protein_coding
  ENSDART00000031408 tcf7l2-009 32668787-32790288 protein_coding
  ENSDART00000121527 tcf7l2-201 32668843-32790099 protein_coding
  ENSDART00000122972 tcf7l2-006 32668787-32790288 protein_coding
  ENSDART00000125046 tcf7l2-008 32668787-32790288 protein_coding
  ENSDART00000128703 tcf7l2-003 32745752-32790049 processed_transcript
  ENSDART00000133854 tcf7l2-005 32676948-32696416 protein_coding
  ENSDART00000145967 tcf7l2-004 32684530-32699842 protein_coding
  ENSDART00000153068 tcf7l2-001 32666837-32790417 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000005562ENSDART00000031408ENSDART00000133854ENSDART00000153068
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000005562 9.525±0.00 N/A N/A N/A N/A
ENSDART00000031408 N/A 0.932±0.00 0.582±0.00 0.171±0.00 0.694±0.00
ENSDART00000133854 N/A N/A N/A 0.257±0.00 N/A
ENSDART00000153068 25.943±1.01 2.059±0.45 1.100±0.00 0.045±0.00 0.539±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IBA chromatin binding
GO:0003700 IBA sequence-specific DNA binding transcription factor activity
GO:0005667 IBA transcription factor complex
GO:0006357 IBA regulation of transcription from RNA polymerase II promoter
GO:0007420 IBA brain development
GO:0008013 IBA beta-catenin binding
GO:0016055 IEA Wnt receptor signaling pathway
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IBA transcription regulatory region DNA binding
GO:0044333 IMP Wnt receptor signaling pathway involved in digestive tract morphogenesis
GO:0048699 IBA generation of neurons
GO:0060070 IMP canonical Wnt receptor signaling pathway
GO:0060729 IMP intestinal epithelial structure maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000148737 TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) protein_coding Homo_sapiens
ENSMUSG00000024985 Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box protein_coding Mus_musculus

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