C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAD homolog 2 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000006389 smad2 7955 - 10:14899576-14971855 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000044756 smad2-201 14901508-14958204 protein_coding
  ENSDART00000121892 smad2-001 14901506-14958204 protein_coding
  ENSDART00000128579 smad2-202 14899576-14949560 protein_coding
  ENSDART00000137430 smad2-003 14949339-14957966 protein_coding
  ENSDART00000143608 smad2-004 14923227-14971855 protein_coding
  ENSDART00000147653 smad2-002 14901679-14958253 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverENSDART00000044756ENSDART00000128579
Transcript ID Brain Heart Liver
ENSDART00000044756 3.402±0.00 3.198±0.00 N/A
ENSDART00000128579 3.745±0.00 N/A 0.223±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IMP sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IMP transcription from RNA polymerase II promoter
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0009880 IMP embryonic pattern specification
GO:0035556 IGI intracellular signal transduction
GO:0046872 IEA metal ion binding
GO:0060282 IMP positive regulation of oocyte development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000175387 SMAD2 SMAD family member 2 protein_coding Homo_sapiens
ENSMUSG00000024563 Smad2 SMAD family member 2 protein_coding Mus_musculus

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