C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: receptor-like tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000007231 ryk 7955 + 6:27222693-27323929 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079397 ryk-001 27222778-27323667 protein_coding
  ENSDART00000128985 ryk-003 27222693-27323929 protein_coding
  ENSDART00000132097 ryk-002 27311799-27322710 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000079397ENSDART00000128985
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000079397 2.158±1.31 3.308±1.36 2.025±1.19 0.478±0.00 1.745±0.00
ENSDART00000128985 0.594±0.01 2.227±0.61 3.748±1.41 0.497±0.00 1.790±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019J CIL_00019J_0001 CGP 6:27222693-27373486

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005622 IMP intracellular
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007223 IMP Wnt receptor signaling pathway, calcium modulating pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017147 IDA Wnt-protein binding
GO:0042074 IMP cell migration involved in gastrulation
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0060026 IGI convergent extension
GO:0060028 IMP convergent extension involved in axis elongation
GO:0060030 IMP dorsal convergence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000163785 RYK receptor-like tyrosine kinase protein_coding Homo_sapiens
ENSMUSG00000032547 Ryk receptor-like tyrosine kinase protein_coding Mus_musculus

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