C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: receptor-like tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163785 RYK 9606 - 3:134065303-134250744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000460933 RYK-009 134157133-134250468 protein_coding
  ENST00000464879 RYK-005 134202537-134207525 retained_intron
  ENST00000472234 RYK-007 134075179-134183033 protein_coding
  ENST00000473208 RYK-006 134157134-134181672 retained_intron
  ENST00000480381 RYK-002 134183002-134195339 retained_intron
  ENST00000481382 RYK-003 134175703-134183403 retained_intron
  ENST00000484106 RYK-008 134065303-134075213 processed_transcript
  ENST00000486725 RYK-004 134159283-134191916 nonsense_mediated_decay
  ENST00000620660 RYK-201 134157134-134250744 protein_coding
  ENST00000623711 RYK-001 134157133-134250744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000460933ENST00000472234ENST00000473208ENST00000620660ENST00000623711
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000460933 14.256±0.00 3.979±0.00 1.452±0.00 1.751±0.00 7.180±4.94 11.210±0.00 2.059±0.00 N/A 2.929±0.00 4.568±0.00 N/A 18.298±1.09 7.908±0.90 21.276±0.00
ENST00000472234 N/A N/A N/A N/A 10.929±0.00 N/A N/A 5.114±0.00 N/A N/A N/A N/A N/A N/A
ENST00000473208 N/A N/A 0.418±0.00 N/A 1.586±0.00 N/A 0.404±0.00 0.464±0.00 N/A 1.206±0.00 0.201±0.00 1.344±0.00 N/A N/A
ENST00000620660 N/A N/A N/A 1.435±0.34 2.785±0.00 5.640±0.00 3.989±0.00 5.603±3.19 6.061±0.00 1.942±0.00 4.486±3.15 5.041±1.61 6.870±0.00 10.531±0.00
ENST00000623711 9.170±0.00 5.253±0.00 0.541±0.00 1.879±0.00 3.339±1.98 3.817±2.45 3.541±2.40 N/A N/A 6.425±0.00 3.034±0.00 5.124±3.30 2.781±0.13 7.491±2.26

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005109 IEA frizzled binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007409 IEA axonogenesis
GO:0007411 IEA axon guidance
GO:0016020 IEA membrane
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017147 IEA Wnt-protein binding
GO:0022038 IEA corpus callosum development
GO:0030182 IEA neuron differentiation
GO:0031175 IEA neuron projection development
GO:0042813 IEA Wnt-activated receptor activity
GO:0048705 IEA skeletal system morphogenesis
GO:0048843 IEA negative regulation of axon extension involved in axon guidance
GO:0050919 IEA negative chemotaxis
GO:0071679 IEA commissural neuron axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007231 ryk receptor-like tyrosine kinase protein_coding Danio_rerio
ENSMUSG00000032547 Ryk receptor-like tyrosine kinase protein_coding Mus_musculus

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