C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: receptor-like tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032547 Ryk 10090 + 9:102834917-102908305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035142 Ryk-001 102834972-102907953 protein_coding
  ENSMUST00000175788 Ryk-004 102869066-102881662 retained_intron
  ENSMUST00000175883 Ryk-003 102834917-102907542 protein_coding
  ENSMUST00000176198 Ryk-002 102834982-102908305 nonsense_mediated_decay
  ENSMUST00000176573 Ryk-006 102845833-102861897 processed_transcript
  ENSMUST00000177274 Ryk-005 102898555-102899546 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035142ENSMUST00000175883
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035142 22.926±3.42 18.324±3.39 22.733±0.13 9.112±5.87 16.958±7.04 20.742±2.99 10.961±0.86 15.514±1.90 7.161±0.87 35.978±1.46 11.386±0.47 26.817±11.78 10.988±4.81 2.875±1.29
ENSMUST00000175883 18.661±1.32 6.119±3.65 11.972±0.33 5.138±1.87 11.460±6.11 6.317±2.01 6.115±0.50 8.507±3.19 3.747±0.78 8.761±2.98 9.121±1.22 11.293±5.64 13.449±3.78 1.172±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00019J CIL_00019J_0002 CGP 9:102834917-103096002

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005109 IPI frizzled binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007409 IGI axonogenesis
GO:0007411 IDA axon guidance
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016055 IGI Wnt signaling pathway
GO:0017147 IPI Wnt-protein binding
GO:0022038 IMP corpus callosum development
GO:0030182 IDA neuron differentiation
GO:0031175 IMP neuron projection development
GO:0042813 IPI Wnt-activated receptor activity
GO:0043410 ISS positive regulation of MAPK cascade
GO:0048705 IMP skeletal system morphogenesis
GO:0048843 IGI negative regulation of axon extension involved in axon guidance
GO:0050919 IGI negative chemotaxis
GO:0071679 IMP commissural neuron axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007231 ryk receptor-like tyrosine kinase protein_coding Danio_rerio
ENSG00000163785 RYK receptor-like tyrosine kinase protein_coding Homo_sapiens

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