C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000012914 arhgef4 7955 - 2:16019318-16179625 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000057216 arhgef4-002 16019318-16179625 protein_coding
  ENSDART00000133708 arhgef4-001 16019318-16075365 protein_coding
  ENSDART00000152031 arhgef4-003 16019318-16037927 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000057216ENSDART00000133708ENSDART00000152031
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000057216 4.818±1.96 2.593±2.03 0.846±0.79 0.049±0.00 0.412±0.00
ENSDART00000133708 19.875±1.23 9.293±8.34 1.421±0.00 0.078±0.00 2.566±0.00
ENSDART00000152031 15.178±0.03 N/A N/A 0.033±0.00 0.938±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000136002 ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 protein_coding Homo_sapiens
ENSMUSG00000037509 Arhgef4 Rho guanine nucleotide exchange factor (GEF) 4 protein_coding Mus_musculus

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