C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000057216 arhgef4-002 ENSDARG00000012914 7955 - 2:16019318-16179625 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000057216
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000057216 4.818±1.96 2.593±2.03 0.846±0.79 0.049±0.00 0.412±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047664 Arhgef4-001 protein_coding Mus_musculus 0 723
ENSMUST00000159021 Arhgef4-006 protein_coding Mus_musculus 0 350
ENSMUST00000159059 Arhgef4-007 retained_intron Mus_musculus 0 222
ENSMUST00000159747 Arhgef4-004 protein_coding Mus_musculus 0 760
ENSMUST00000160855 Arhgef4-003 nonsense_mediated_decay Mus_musculus 0 222
ENSMUST00000162599 Arhgef4-005 protein_coding Mus_musculus 0 224
ENSMUST00000162760 Arhgef4-002 retained_intron Mus_musculus 0 433

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