C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone deacetylase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000015427 hdac1 7955 + 19:31054097-31064046 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000051799 hdac1-001 31054097-31064046 protein_coding
  ENSDART00000148935 hdac1-004 31054111-31060236 retained_intron
  ENSDART00000149128 hdac1-005 31060180-31061130 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000051799
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000051799 28.462±16.97 18.118±14.52 26.905±14.53 5.882±0.00 11.474±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002A7 CIL_0002A7_0001 CGP 19:31043504-31064046

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0001889 IMP liver development
GO:0004407 IEA histone deacetylase activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0008285 IMP negative regulation of cell proliferation
GO:0016055 IGI Wnt receptor signaling pathway
GO:0016568 IEA chromatin modification
GO:0016575 IEA histone deacetylation
GO:0016787 IEA hydrolase activity
GO:0021754 IMP facial nucleus development
GO:0021903 IMP rostrocaudal neural tube patterning
GO:0030318 IMP melanocyte differentiation
GO:0031017 IMP exocrine pancreas development
GO:0031078 IEA histone deacetylase activity (H3-K14 specific)
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032129 IEA histone deacetylase activity (H3-K9 specific)
GO:0034739 IEA histone deacetylase activity (H4-K16 specific)
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048263 IMP determination of dorsal identity
GO:0048565 IMP digestive tract development
GO:0048709 IMP oligodendrocyte differentiation
GO:0050769 IMP positive regulation of neurogenesis
GO:0060028 IMP convergent extension involved in axis elongation
GO:0060042 IGI retina morphogenesis in camera-type eye
GO:0060218 IMP hematopoietic stem cell differentiation
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000116478 HDAC1 histone deacetylase 1 protein_coding Homo_sapiens
ENSMUSG00000028800 Hdac1 histone deacetylase 1 protein_coding Mus_musculus
ENSMUSG00000061062 Gm10093 predicted pseudogene 10093 protein_coding Mus_musculus

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