C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: rho-associated, coiled-coil containing protein kinase 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000017500 rock2a 7955 - 13:33038843-33122924 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000133882 rock2a-001 33038843-33122924 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000133882
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000133882 3.748±2.75 20.723±13.64 4.312±3.69 0.379±0.00 2.216±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001X CIL_00001X_0001 CGP 13:33031021-33122924

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005773 IPI vacuole
GO:0005886 IDA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007039 IPI vacuolar protein catabolic process
GO:0007165 IEA signal transduction
GO:0016055 IMP Wnt receptor signaling pathway
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017048 IEA Rho GTPase binding
GO:0030163 IPI protein catabolic process
GO:0032956 IMP regulation of actin cytoskeleton organization
GO:0035556 IEA intracellular signal transduction
GO:0042074 IMP cell migration involved in gastrulation
GO:0046872 IEA metal ion binding
GO:0048333 IGI mesodermal cell differentiation
GO:0060031 IMP mediolateral intercalation
GO:0060775 IMP planar cell polarity pathway involved in gastrula mediolateral intercalation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000134318 ROCK2 Rho-associated, coiled-coil containing protein kinase 2 protein_coding Homo_sapiens
ENSMUSG00000020580 Rock2 Rho-associated coiled-coil containing protein kinase 2 protein_coding Mus_musculus

Loading