C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 transcription factor related 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000018004 nkx2.5 7955 + 14:25240905-25243698 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000022377 nkx2.5-001 25240905-25243698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000022377
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000022377 2.345±1.11 81.682±22.66 2.914±1.50 0.062±0.00 0.186±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001947 IGI heart looping
GO:0003007 IGI heart morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007507 IGI heart development
GO:0035050 IMP embryonic heart tube development
GO:0043565 IEA sequence-specific DNA binding
GO:0055007 IGI cardiac muscle cell differentiation
GO:0060038 IGI cardiac muscle cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000183072 NKX2-5 NK2 homeobox 5 protein_coding Homo_sapiens
ENSMUSG00000015579 Nkx2-5 NK2 homeobox 5 protein_coding Mus_musculus

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