C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NK2 transcription factor related 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000022377 nkx2.5-001 ENSDARG00000018004 7955 + 14:25240905-25243698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000022377
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000022377 2.345±1.11 81.682±22.66 2.914±1.50 0.062±0.00 0.186±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001947 IGI heart looping
GO:0003007 IGI heart morphogenesis
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007507 IGI heart development
GO:0035050 IMP embryonic heart tube development
GO:0043565 IEA sequence-specific DNA binding
GO:0055007 IGI cardiac muscle cell differentiation
GO:0060038 IGI cardiac muscle cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000354822 NKX2-1-002 protein_coding Homo_sapiens 5e-29 134
ENST00000498187 NKX2-1-001 protein_coding Homo_sapiens 5e-29 134
ENST00000518149 NKX2-1-004 protein_coding Homo_sapiens 6e-29 134
ENST00000522719 NKX2-1-003 protein_coding Homo_sapiens 3e-29 134

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