C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000019371 flt1 7955 - 24:22358758-22416767 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000025621 flt1-001 22358758-22416764 protein_coding
  ENSDART00000130446 flt1-002 22388496-22416767 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000025621ENSDART00000130446
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000025621 2.025±1.04 2.553±0.92 0.382±0.00 0.293±0.00 1.333±0.00
ENSDART00000130446 6.551±1.43 13.786±6.50 1.177±1.12 0.943±0.00 9.930±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000G1 CIL_0000G1_0001 CGP 24:22328252-22416767

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001570 IMP vasculogenesis
GO:0002040 IMP sprouting angiogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005021 IEA vascular endothelial growth factor-activated receptor activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IEA integral to plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008016 IMP regulation of heart contraction
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000102755 FLT1 fms-related tyrosine kinase 1 protein_coding Homo_sapiens
ENSMUSG00000029648 Flt1 FMS-like tyrosine kinase 1 protein_coding Mus_musculus

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