C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal transduction and activation of transcription 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000022712 stat3 7955 + 3:16650646-16727426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000080854 stat3-002 16650685-16727212 protein_coding
  ENSDART00000104519 stat3-001 16650646-16727426 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000080854ENSDART00000104519
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000080854 2.183±0.00 3.005±0.00 N/A 7.267±0.00 2.556±0.00
ENSDART00000104519 N/A 15.251±3.14 30.317±0.00 2.044±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001736 IMP establishment of planar polarity
GO:0001837 IMP epithelial to mesenchymal transition
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005622 IMP intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007165 IEA signal transduction
GO:0007259 IMP JAK-STAT cascade
GO:0008045 IMP motor neuron axon guidance
GO:0030010 IMP establishment of cell polarity
GO:0042074 IMP cell migration involved in gastrulation
GO:0060042 IMP retina morphogenesis in camera-type eye
GO:0060252 IMP positive regulation of glial cell proliferation
GO:0061026 IMP cardiac muscle tissue regeneration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000168610 STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) protein_coding Homo_sapiens
ENSMUSG00000004040 Stat3 signal transducer and activator of transcription 3 protein_coding Mus_musculus

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