C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatase and actin regulator 4b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000032221 phactr4b 7955 - 16:36615379-36702455 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000044235 phactr4b-001 36616646-36702455 protein_coding
  ENSDART00000081066 phactr4b-201 36615379-36682927 protein_coding
  ENSDART00000145017 phactr4b-003 36622544-36630261 protein_coding
  ENSDART00000145485 phactr4b-002 36651461-36676280 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartLiverMuscleENSDART00000044235ENSDART00000081066
Transcript ID Brain Heart Liver Muscle
ENSDART00000044235 N/A N/A 0.135±0.00 0.551±0.00
ENSDART00000081066 2.080±0.00 3.018±1.98 N/A 1.360±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001RA CIL_0001RA_0001 CGP 16:36602962-36702455

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001755 ISS neural crest cell migration
GO:0001843 ISS neural tube closure
GO:0003779 ISS actin binding
GO:0005622 ISS intracellular
GO:0005737 IEA cytoplasm
GO:0007266 ISS Rho protein signal transduction
GO:0007275 IEA multicellular organismal development
GO:0007399 IEA nervous system development
GO:0008157 ISS protein phosphatase 1 binding
GO:0030027 ISS lamellipodium
GO:0030036 ISS actin cytoskeleton organization
GO:0042995 IEA cell projection
GO:0043085 ISS positive regulation of catalytic activity
GO:0048484 ISS enteric nervous system development
GO:0051726 ISS regulation of cell cycle
GO:0061386 ISS closure of optic fissure
GO:0071862 ISS protein phosphatase type 1 activator activity
GO:2001045 ISS negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000204138 PHACTR4 phosphatase and actin regulator 4 protein_coding Homo_sapiens
ENSMUSG00000066043 Phactr4 phosphatase and actin regulator 4 protein_coding Mus_musculus

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