C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatase and actin regulator 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000066043 Phactr4 10090 - 4:132355923-132422489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084170 Phactr4-201 132355930-132422446 protein_coding
  ENSMUST00000084249 Phactr4-002 132358249-132398211 protein_coding
  ENSMUST00000102568 Phactr4-001 132355923-132422489 protein_coding
  ENSMUST00000127516 Phactr4-005 132360677-132370531 processed_transcript
  ENSMUST00000136711 Phactr4-004 132377461-132398199 protein_coding
  ENSMUST00000152271 Phactr4-003 132370951-132422441 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084170ENSMUST00000084249ENSMUST00000102568ENSMUST00000127516ENSMUST00000136711
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084170 2.446±1.39 4.012±2.64 2.839±0.00 2.924±2.47 1.052±0.48 5.123±2.80 2.396±1.63 7.284±3.36 2.984±1.23 3.984±2.30 0.749±0.19 3.506±1.60 4.721±1.74 1.508±0.32
ENSMUST00000084249 N/A 1.898±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000102568 0.335±0.00 0.752±0.00 1.278±0.79 0.752±0.12 0.963±0.00 2.127±0.53 0.688±0.00 2.088±0.47 1.673±0.73 1.376±0.23 2.147±0.43 2.675±1.87 5.431±2.38 0.965±0.30
ENSMUST00000127516 N/A N/A N/A 5.853±0.00 N/A N/A N/A N/A N/A N/A N/A 27.145±0.00 29.688±5.74 19.334±0.00
ENSMUST00000136711 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.684±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099N CIL_00099N_0002 VISTA 4:131775516-132379227
CIL_0001RA CIL_0001RA_0002 CGP 4:132331919-132422489

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0001843 IMP neural tube closure
GO:0003779 IDA actin binding
GO:0004864 IEA protein phosphatase inhibitor activity
GO:0005622 IMP intracellular
GO:0005737 IEA cytoplasm
GO:0007266 IMP Rho protein signal transduction
GO:0008157 IDA protein phosphatase 1 binding
GO:0030027 IDA lamellipodium
GO:0030036 IMP actin cytoskeleton organization
GO:0043085 IDA positive regulation of catalytic activity
GO:0043086 IEA negative regulation of catalytic activity
GO:0048484 IMP enteric nervous system development
GO:0051726 IMP regulation of cell cycle
GO:0061386 IMP closure of optic fissure
GO:0071862 IDA protein phosphatase type 1 activator activity
GO:2001045 IMP negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015552 phactr4a phosphatase and actin regulator 4a protein_coding Danio_rerio
ENSDARG00000032221 phactr4b phosphatase and actin regulator 4b protein_coding Danio_rerio
ENSG00000204138 PHACTR4 phosphatase and actin regulator 4 protein_coding Homo_sapiens

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