C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosyl-DNA phosphodiesterase 2b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000035954 tdp2b 7955 - 19:32814390-32821719 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000103612 tdp2b-001 32814390-32821719 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000103612
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000103612 1.467±0.41 1.376±0.64 6.621±2.98 0.387±0.00 0.936±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036U CIL_00036U_0001 CGP 19:32814390-32824781

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0003677 IDA DNA binding
GO:0003697 ISS single-stranded DNA binding
GO:0004518 IEA nuclease activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0006281 IEA DNA repair
GO:0006302 ISS double-strand break repair
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007275 IEA multicellular organismal development
GO:0007368 IMP determination of left/right symmetry
GO:0007369 IMP gastrulation
GO:0016605 ISS PML body
GO:0016787 IEA hydrolase activity
GO:0030145 ISS manganese ion binding
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0046872 IEA metal ion binding
GO:0060027 IMP convergent extension involved in gastrulation
GO:0070260 ISS 5'-tyrosyl-DNA phosphodiesterase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000111802 TDP2 tyrosyl-DNA phosphodiesterase 2 protein_coding Homo_sapiens
ENSMUSG00000035958 Tdp2 tyrosyl-DNA phosphodiesterase 2 protein_coding Mus_musculus

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