C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosyl-DNA phosphodiesterase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035958 Tdp2 10090 + 13:24831679-24842153 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038039 Tdp2-001 24831679-24842153 protein_coding
  ENSMUST00000130788 Tdp2-002 24831822-24838265 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038039
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038039 3.684±1.17 4.455±1.47 7.475±2.05 9.819±6.49 3.672±2.00 5.785±0.82 2.543±0.35 7.404±1.11 11.357±5.64 4.218±0.67 2.624±0.53 5.450±1.80 9.227±5.72 6.851±2.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000LD CIL_0000LD_0002 CGP 13:24831679-24901270

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0003697 ISS single-stranded DNA binding
GO:0004519 ISA endonuclease activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006302 ISS double-strand break repair
GO:0008081 ISA phosphoric diester hydrolase activity
GO:0016605 ISS PML body
GO:0030145 ISS manganese ion binding
GO:0036317 IEA tyrosyl-RNA phosphodiesterase activity
GO:0045171 IEA intercellular bridge
GO:0070260 ISS 5'-tyrosyl-DNA phosphodiesterase activity
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035954 tdp2b tyrosyl-DNA phosphodiesterase 2b protein_coding Danio_rerio
ENSDARG00000069941 TDP2 (2 of 2) tyrosyl-DNA phosphodiesterase 2 protein_coding Danio_rerio
ENSG00000111802 TDP2 tyrosyl-DNA phosphodiesterase 2 protein_coding Homo_sapiens

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