C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosyl-DNA phosphodiesterase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111802 TDP2 9606 - 6:24649977-24667033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341060 TDP2-002 24649979-24666591 protein_coding
  ENST00000378198 TDP2-001 24649977-24667033 protein_coding
  ENST00000478285 TDP2-004 24654378-24659172 processed_transcript
  ENST00000478507 TDP2-005 24650987-24666930 processed_transcript
  ENST00000480495 TDP2-003 24665987-24666786 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000341060ENST00000378198ENST00000478285ENST00000478507
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000341060 N/A N/A 1.434±0.00 N/A 1.357±0.00 N/A N/A N/A N/A 1.322±0.00 N/A 2.005±0.00 N/A N/A
ENST00000378198 10.199±0.00 8.110±0.00 2.974±0.00 9.699±2.50 10.047±3.03 24.318±2.05 5.239±3.33 13.516±10.82 8.021±1.59 6.732±2.11 2.282±1.62 10.317±1.08 6.628±0.78 14.229±8.93
ENST00000478285 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.773±0.00 0.318±0.00 N/A N/A N/A
ENST00000478507 10.607±0.00 N/A N/A 14.969±0.00 N/A N/A N/A N/A N/A N/A N/A 11.547±0.00 10.309±0.00 8.552±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00036U CIL_00036U_0002 CGP 6:24649977-24705065

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 TAS magnesium ion binding
GO:0003697 IDA single-stranded DNA binding
GO:0003714 TAS transcription corepressor activity
GO:0004518 IEA nuclease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006302 IDA double-strand break repair
GO:0007166 TAS cell surface receptor signaling pathway
GO:0016605 IDA PML body
GO:0030145 IDA manganese ion binding
GO:0036317 IDA tyrosyl-RNA phosphodiesterase activity
GO:0045171 IDA intercellular bridge
GO:0070260 IDA 5'-tyrosyl-DNA phosphodiesterase activity
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:2001141 TAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035954 tdp2b tyrosyl-DNA phosphodiesterase 2b protein_coding Danio_rerio
ENSDARG00000069941 TDP2 (2 of 2) tyrosyl-DNA phosphodiesterase 2 protein_coding Danio_rerio
ENSMUSG00000035958 Tdp2 tyrosyl-DNA phosphodiesterase 2 protein_coding Mus_musculus

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