C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000037116 cxcl12a 7955 + 13:31027969-31043317 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000053946 cxcl12a-001 31027969-31043317 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000053946
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000053946 16.666±4.06 17.859±5.30 320.603±132.52 1.126±0.00 75.508±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00055S CIL_00055S_0001 CGP 13:30927963-31043317

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IGI cell morphogenesis
GO:0001764 IMP neuron migration
GO:0005576 IEA extracellular region
GO:0006955 IEA immune response
GO:0007411 IMP axon guidance
GO:0008009 IEA chemokine activity
GO:0008285 IDA negative regulation of cell proliferation
GO:0008354 IMP germ cell migration
GO:0009887 IMP organ morphogenesis
GO:0030239 IMP myofibril assembly
GO:0030335 IMP positive regulation of cell migration
GO:0030516 IMP regulation of axon extension
GO:0030900 IMP forebrain development
GO:0031101 IMP fin regeneration
GO:0031290 IGI retinal ganglion cell axon guidance
GO:0042056 IDA chemoattractant activity
GO:0042074 IMP cell migration involved in gastrulation
GO:0048842 IDA positive regulation of axon extension involved in axon guidance
GO:0048920 IMP posterior lateral line neuromast primordium migration
GO:0050918 IMP positive chemotaxis
GO:0050930 IMP induction of positive chemotaxis
GO:0055002 IMP striated muscle cell development
GO:0090024 IGI negative regulation of neutrophil chemotaxis
GO:2000472 IGI negative regulation of hematopoietic stem cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000107562 CXCL12 chemokine (C-X-C motif) ligand 12 protein_coding Homo_sapiens
ENSMUSG00000061353 Cxcl12 chemokine (C-X-C motif) ligand 12 protein_coding Mus_musculus

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