C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: core-binding factor, beta subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000040917 cbfb 7955 + 18:22774824-22852023 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000059961 cbfb-001 22774824-22852023 protein_coding
  ENSDART00000141521 cbfb-002 22836511-22852023 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000059961ENSDART00000141521
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000059961 1.028±0.00 N/A N/A 0.121±0.00 1.250±0.00
ENSDART00000141521 1.653±0.96 1.525±0.51 3.386±0.67 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001076 IC RNA polymerase II transcription factor binding transcription factor activity
GO:0003677 IPI DNA binding
GO:0003713 IEA transcription coactivator activity
GO:0005634 IEA nucleus
GO:0006357 IC regulation of transcription from RNA polymerase II promoter
GO:0006366 IC transcription from RNA polymerase II promoter
GO:0016513 IPI core-binding factor complex
GO:0030018 IDA Z disc
GO:0045214 IMP sarcomere organization
GO:0046982 IPI protein heterodimerization activity
GO:0048769 IMP sarcomerogenesis
GO:0060047 IMP heart contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000067955 CBFB core-binding factor, beta subunit protein_coding Homo_sapiens
ENSMUSG00000031885 Cbfb core binding factor beta protein_coding Mus_musculus

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