C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box O3b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000042904 foxo3b 7955 - 20:32323909-32371617 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000062982 foxo3b-001 32325646-32371617 protein_coding
  ENSDART00000125597 foxo3b-201 32329971-32370206 protein_coding
  ENSDART00000126370 foxo3b-202 32323909-32370053 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000062982ENSDART00000126370
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000062982 5.788±1.43 22.271±0.00 1.785±0.00 1.448±0.00 N/A
ENSDART00000126370 25.659±10.25 10.884±1.65 N/A 1.186±0.00 17.301±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00034X CIL_00034X_0001 CGP 20:32267091-32371617

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005829 IBA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006974 IBA cellular response to DNA damage stimulus
GO:0007389 IBA pattern specification process
GO:0008286 IBA insulin receptor signaling pathway
GO:0008301 IBA DNA binding, bending
GO:0009790 IMP embryo development
GO:0009888 IBA tissue development
GO:0019901 IBA protein kinase binding
GO:0030178 IPI negative regulation of Wnt receptor signaling pathway
GO:0042127 IBA regulation of cell proliferation
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IBA positive regulation of transcription from RNA polymerase II promoter
GO:0048513 IBA organ development
GO:0090090 IDA negative regulation of canonical Wnt receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000118689 FOXO3 forkhead box O3 protein_coding Homo_sapiens
ENSMUSG00000048756 Foxo3 forkhead box O3 protein_coding Mus_musculus

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