C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000045308 pola1 7955 + 24:24448797-24540473 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000127188 pola1-001 24448797-24540473 protein_coding
  ENSDART00000128595 pola1-201 24448900-24540472 protein_coding
  ENSDART00000138097 pola1-002 24449632-24540473 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000127188ENSDART00000128595ENSDART00000138097
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000127188 0.794±0.41 0.773±0.00 1.872±0.00 0.232±0.00 N/A
ENSDART00000128595 0.870±0.25 0.262±0.00 2.024±2.62 N/A 0.345±0.00
ENSDART00000138097 N/A 0.223±0.00 N/A 0.242±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001X9 CIL_0001X9_0001 CGP 24:24448797-24550670

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001882 IEA nucleoside binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003887 IEA DNA-directed DNA polymerase activity
GO:0005634 IBA nucleus
GO:0005658 IBA alpha DNA polymerase:primase complex
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006260 IEA DNA replication
GO:0006261 IBA DNA-dependent DNA replication
GO:0006303 IBA double-strand break repair via nonhomologous end joining
GO:0008408 IBA 3'-5' exonuclease activity
GO:0016740 IEA transferase activity
GO:0016779 IEA nucleotidyltransferase activity
GO:0019985 IBA translesion synthesis
GO:0090305 IBA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000101868 POLA1 polymerase (DNA directed), alpha 1, catalytic subunit protein_coding Homo_sapiens
ENSMUSG00000006678 Pola1 polymerase (DNA directed), alpha 1 protein_coding Mus_musculus

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