C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052734 hmgcra 7955 - 5:52658957-52678922 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000097460 hmgcra-001 52658957-52678922 protein_coding
  ENSDART00000149553 hmgcra-002 52659897-52678901 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000097460ENSDART00000149553
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000097460 1.406±0.93 0.349±0.00 3.004±0.00 1.011±0.00 0.363±0.00
ENSDART00000149553 1.062±0.03 0.142±0.07 3.777±0.00 1.883±0.00 0.276±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XB CIL_0002XB_0001 CGP 5:52599245-52678922

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004420 IEA hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0005789 IEA endoplasmic reticulum membrane
GO:0007517 IMP muscle organ development
GO:0008158 IEA hedgehog receptor activity
GO:0008299 IEA isoprenoid biosynthetic process
GO:0015936 IEA coenzyme A metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0050661 IEA NADP binding
GO:0050662 IEA coenzyme binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113161 HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase protein_coding Homo_sapiens
ENSMUSG00000021670 Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase protein_coding Mus_musculus

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