C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: topoisomerase (DNA) III alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052827 top3a 7955 - 3:40230070-40249416 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000102492 top3a-201 40230167-40249227 protein_coding
  ENSDART00000154562 top3a-001 40230070-40249416 protein_coding
  ENSDART00000155667 top3a-002 40246198-40246727 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000102492ENSDART00000154562ENSDART00000155667
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000102492 0.263±0.09 1.403±0.00 0.359±0.00 0.109±0.00 N/A
ENSDART00000154562 0.350±0.23 0.319±0.06 1.152±1.09 N/A 0.265±0.00
ENSDART00000155667 N/A 1.410±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00002B CIL_00002B_0001 CGP 3:40230070-40253732

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003916 IEA DNA topoisomerase activity
GO:0003917 IEA DNA topoisomerase type I activity
GO:0005694 IEA chromosome
GO:0006265 IEA DNA topological change
GO:0008270 IEA zinc ion binding
GO:0016853 IEA isomerase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000177302 TOP3A topoisomerase (DNA) III alpha protein_coding Homo_sapiens
ENSMUSG00000002814 Top3a topoisomerase (DNA) III alpha protein_coding Mus_musculus

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