C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Werner syndrome
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000053065 wrn 7955 - 10:6081678-6153793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000074986 wrn-201 6081856-6153459 protein_coding
  ENSDART00000136531 wrn-001 6081678-6153793 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartKidneyLiverMuscleENSDART00000074986ENSDART00000136531
Transcript ID Heart Kidney Liver Muscle
ENSDART00000074986 0.427±0.00 1.098±0.00 0.063±0.00 0.094±0.00
ENSDART00000136531 N/A 0.245±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KM CIL_0006KM_0001 CGP 10:5882254-6153793
CIL_0006KJ CIL_0006KJ_0001 CGP 10:6081678-6163207

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003676 IEA nucleic acid binding
GO:0003824 IEA catalytic activity
GO:0004386 IEA helicase activity
GO:0005524 IEA ATP binding
GO:0005622 IEA intracellular
GO:0006139 IEA nucleobase-containing compound metabolic process
GO:0006260 IEA DNA replication
GO:0006281 IEA DNA repair
GO:0006310 IEA DNA recombination
GO:0008026 IEA ATP-dependent helicase activity
GO:0008408 IEA 3'-5' exonuclease activity
GO:0016787 IEA hydrolase activity
GO:0043140 IEA ATP-dependent 3'-5' DNA helicase activity
GO:0044237 IEA cellular metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000165392 WRN Werner syndrome, RecQ helicase-like protein_coding Homo_sapiens
ENSMUSG00000031583 Wrn Werner syndrome homolog (human) protein_coding Mus_musculus

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