C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malic enzyme 1, NADP(+)-dependent, cytosolic
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000053215 me1 7955 - 16:35157785-35314738 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000075218 me1-201 35157791-35314731 protein_coding
  ENSDART00000101969 me1-002 35157785-35290379 protein_coding
  ENSDART00000147941 me1-001 35157785-35314738 protein_coding
  ENSDART00000149096 me1-003 35202507-35290386 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000075218ENSDART00000101969ENSDART00000147941ENSDART00000149096
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000075218 0.081±0.05 1.036±0.12 2.495±0.00 0.347±0.00 N/A
ENSDART00000101969 0.130±0.14 5.484±2.91 4.506±0.00 0.380±0.00 2.068±0.00
ENSDART00000147941 0.033±0.00 N/A N/A N/A N/A
ENSDART00000149096 N/A 7.711±2.88 12.887±0.00 0.916±0.00 3.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000625 CIL_000625_0001 CGP 16:35157785-35318475

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004470 IEA malic enzyme activity
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0005575 ND cellular_component
GO:0006108 IEA malate metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 IEA metal ion binding
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000065833 ME1 malic enzyme 1, NADP(+)-dependent, cytosolic protein_coding Homo_sapiens
ENSMUSG00000032418 Me1 malic enzyme 1, NADP(+)-dependent, cytosolic protein_coding Mus_musculus

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