C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malic enzyme 1, NADP(+)-dependent, cytosolic
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032418 Me1 10090 - 9:86581371-86695953 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034989 Me1-001 86581371-86695953 protein_coding
  ENSMUST00000185374 Me1-002 86581406-86687277 protein_coding
  ENSMUST00000189847 Me1-004 86613541-86618737 processed_transcript
  ENSMUST00000189968 Me1-003 86582686-86618704 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034989ENSMUST00000185374ENSMUST00000189968
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034989 224.349±46.09 247.709±70.17 48.890±3.86 9.610±3.99 156.581±73.04 5.750±1.13 33.918±1.64 79.519±4.43 18.874±18.87 23.656±4.42 77.364±7.69 116.599±58.17 17.791±5.40 66.651±15.91
ENSMUST00000185374 90.408±5.15 110.458±10.29 N/A N/A 157.584±69.71 N/A N/A N/A 5.882±0.61 13.110±5.04 N/A 44.105±11.55 N/A N/A
ENSMUST00000189968 100.185±0.00 N/A N/A 22.062±0.00 102.331±0.00 N/A 13.571±0.00 35.615±0.00 19.409±15.60 15.191±0.07 N/A 149.701±119.46 28.114±15.24 62.713±40.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000670 CIL_000670_0002 CGP 9:86571991-86695953
CIL_000625 CIL_000625_0003 CGP 9:86581371-86758443

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004470 ISS malic enzyme activity
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 ISS malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0006108 ISS malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0009725 ISS response to hormone
GO:0030145 ISS manganese ion binding
GO:0051262 IDA protein tetramerization
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053215 me1 malic enzyme 1, NADP(+)-dependent, cytosolic protein_coding Danio_rerio
ENSDARG00000086961 ME1 (2 of 2) malic enzyme 1, NADP(+)-dependent, cytosolic protein_coding Danio_rerio
ENSG00000065833 ME1 malic enzyme 1, NADP(+)-dependent, cytosolic protein_coding Homo_sapiens

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