C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000055577 chrm2a 7955 + 4:1011358-1204445 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000077955 chrm2a-001 1011358-1204445 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000077955
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000077955 4.387±3.09 5.654±4.47 0.730±0.00 0.833±0.00 0.119±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00023Q CIL_00023Q_0001 CGP 4:1011358-1280268

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 IEA signal transducer activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005887 IEA integral to plasma membrane
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0008016 IEA regulation of heart contraction
GO:0010459 IMP negative regulation of heart rate
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016907 IEA G-protein coupled acetylcholine receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000181072 CHRM2 cholinergic receptor, muscarinic 2 protein_coding Homo_sapiens
ENSMUSG00000045613 Chrm2 cholinergic receptor, muscarinic 2, cardiac protein_coding Mus_musculus

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