C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181072 CHRM2 9606 + 7:136868669-137020255 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320658 CHRM2-007 136869085-137016266 protein_coding
  ENST00000401861 CHRM2-003 136869122-137017024 protein_coding
  ENST00000445907 CHRM2-001 136868669-137020255 protein_coding
  ENST00000453373 CHRM2-004 136869085-137016642 protein_coding
  ENST00000471195 CHRM2-005 136868778-136869884 processed_transcript
  ENST00000480591 CHRM2-002 136869085-136871963 processed_transcript
  ENST00000481598 CHRM2-006 136869085-136870171 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000320658ENST00000445907ENST00000453373ENST00000471195
Transcript ID Adipose Brain Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000320658 0.007±0.00 N/A N/A N/A 0.069±0.00 N/A N/A N/A N/A 0.086±0.00
ENST00000445907 0.002±0.00 0.272±0.00 2.970±1.61 1.583±0.44 0.021±0.00 4.418±0.00 0.155±0.00 0.041±0.02 0.041±0.00 N/A
ENST00000453373 N/A N/A N/A N/A N/A N/A 0.187±0.00 N/A N/A N/A
ENST00000471195 N/A 2.045±0.00 N/A N/A N/A N/A 2.085±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00023Q CIL_00023Q_0002 CGP 7:136868669-137343865

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004930 IEA G-protein coupled receptor activity
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0007186 TAS:IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007207 TAS phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0007213 IDA G-protein coupled acetylcholine receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0008016 IEA regulation of heart contraction
GO:0009615 IEP response to virus
GO:0016021 IEA integral component of membrane
GO:0016907 IDA G-protein coupled acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0045211 IEA postsynaptic membrane
GO:0051482 IDA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029994 chrm2b cholinergic receptor, muscarinic 2b protein_coding Danio_rerio
ENSDARG00000055577 chrm2a cholinergic receptor, muscarinic 2a protein_coding Danio_rerio
ENSMUSG00000045613 Chrm2 cholinergic receptor, muscarinic 2, cardiac protein_coding Mus_musculus

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