C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cholinergic receptor, muscarinic 2, cardiac
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045613 Chrm2 10090 + 6:36388084-36528414 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000169004 Chrm2-002 36388195-36444497 processed_transcript
  ENSMUST00000172278 Chrm2-001 36388084-36528414 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000169004ENSMUST00000172278
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000169004 0.055±0.00 N/A N/A N/A 0.139±0.00 N/A N/A 0.052±0.00 N/A N/A N/A 0.232±0.00 N/A 0.064±0.00
ENSMUST00000172278 0.013±0.01 0.050±0.02 2.211±0.31 1.165±0.46 0.097±0.05 2.972±0.97 16.362±2.58 0.034±0.02 0.099±0.08 4.140±0.47 0.010±0.00 0.040±0.02 0.060±0.05 0.037±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00023Q CIL_00023Q_0003 CGP 6:36388084-36811361

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005886 IEA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007213 ISS G-protein coupled acetylcholine receptor signaling pathway
GO:0008016 IEA regulation of heart contraction
GO:0009615 IEA response to virus
GO:0016907 ISS G-protein coupled acetylcholine receptor activity
GO:0030054 IEA cell junction
GO:0045211 IEA postsynaptic membrane
GO:0051482 ISS positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029994 chrm2b cholinergic receptor, muscarinic 2b protein_coding Danio_rerio
ENSDARG00000055577 chrm2a cholinergic receptor, muscarinic 2a protein_coding Danio_rerio
ENSG00000181072 CHRM2 cholinergic receptor, muscarinic 2 protein_coding Homo_sapiens

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