C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000068006 gck 7955 + 8:42670732-42682693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000085559 gck-001 42670732-42678791 protein_coding
  ENSDART00000129772 gck-201 42670788-42682693 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000085559ENSDART00000129772
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000085559 0.128±0.00 0.038±0.00 1.054±0.00 1.274±0.00 N/A
ENSDART00000129772 0.099±0.00 0.241±0.21 1.510±0.00 2.468±0.00 0.266±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I9 CIL_0006I9_0001 CGP 8:42650575-42682693

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001678 IBA cellular glucose homeostasis
GO:0004340 IBA glucokinase activity
GO:0004396 IEA hexokinase activity
GO:0005524 IEA ATP binding
GO:0005829 IBA cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006096 IEA glycolysis
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0046835 IBA carbohydrate phosphorylation
GO:0050796 IBA regulation of insulin secretion
GO:0051156 IBA glucose 6-phosphate metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000106633 GCK glucokinase (hexokinase 4) protein_coding Homo_sapiens
ENSMUSG00000041798 Gck glucokinase protein_coding Mus_musculus

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