C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glucokinase (hexokinase 4, maturity onset diabetes of the young 2)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000129772 gck-201 ENSDARG00000068006 7955 + 8:42670788-42682693 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000129772
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000129772 0.099±0.00 0.241±0.21 1.510±0.00 2.468±0.00 0.266±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I9 CIL_0006I9_0001 CGP 8:42650575-42682693

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001678 IBA cellular glucose homeostasis
GO:0004340 IBA glucokinase activity
GO:0004396 IEA hexokinase activity
GO:0005524 IEA ATP binding
GO:0005829 IBA cytosol
GO:0005975 IEA carbohydrate metabolic process
GO:0006096 IEA glycolysis
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016773 IEA phosphotransferase activity, alcohol group as acceptor
GO:0046835 IBA carbohydrate phosphorylation
GO:0050796 IBA regulation of insulin secretion
GO:0051156 IBA glucose 6-phosphate metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000345378 GCK-002 protein_coding Homo_sapiens 0 508
ENST00000395796 GCK-003 protein_coding Homo_sapiens 0 508
ENST00000403799 GCK-001 protein_coding Homo_sapiens 0 508
ENST00000437084 GCK-004 protein_coding Homo_sapiens 0 342
ENST00000616242 GCK-201 protein_coding Homo_sapiens 0 508

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