C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine hydroxymethyltransferase 2 (mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000068724 shmt2 7955 + 6:59094231-59150417 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000099503 shmt2-201 59116225-59148579 protein_coding
  ENSDART00000111064 shmt2-202 59094231-59150417 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000099503ENSDART00000111064
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000099503 N/A 0.779±0.00 N/A 2.361±0.00 N/A
ENSDART00000111064 4.683±1.01 1.532±1.04 3.900±1.70 3.599±0.00 3.173±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002KV CIL_0002KV_0001 CGP 6:59051323-59150417
CIL_0002KW CIL_0002KW_0001 CGP 6:59094231-59189026

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005739 IDA mitochondrion
GO:0006544 IEA glycine metabolic process
GO:0006563 IEA L-serine metabolic process
GO:0008168 IEA methyltransferase activity
GO:0016740 IEA transferase activity
GO:0030170 IEA pyridoxal phosphate binding
GO:0032259 IEA methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000182199 SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) protein_coding Homo_sapiens
ENSMUSG00000025403 Shmt2 serine hydroxymethyltransferase 2 (mitochondrial) protein_coding Mus_musculus

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