C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine hydroxymethyltransferase 2 (mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025403 Shmt2 10090 - 10:127517123-127522444 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026470 Shmt2-201 127517123-127522444 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026470
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026470 16.175±3.02 32.375±8.36 21.591±2.74 17.377±11.89 11.875±5.37 12.048±1.72 12.964±1.88 78.756±13.00 73.954±23.77 11.342±2.64 7.699±2.01 24.232±9.30 28.703±17.83 4.003±1.87

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0004372 IEA glycine hydroxymethyltransferase activity
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005758 IEA mitochondrial intermembrane space
GO:0005759 IEA mitochondrial matrix
GO:0006545 IEA glycine biosynthetic process
GO:0006564 IEA L-serine biosynthetic process
GO:0006730 IEA one-carbon metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0008732 IEA L-allo-threonine aldolase activity
GO:0015630 IEA microtubule cytoskeleton
GO:0016597 IEA amino acid binding
GO:0019264 IEA glycine biosynthetic process from serine
GO:0030170 IEA pyridoxal phosphate binding
GO:0035999 IEA tetrahydrofolate interconversion
GO:0042645 IEA mitochondrial nucleoid
GO:0042802 IEA identical protein binding
GO:0051289 IEA protein homotetramerization
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068724 shmt2 serine hydroxymethyltransferase 2 (mitochondrial) protein_coding Danio_rerio
ENSG00000182199 SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) protein_coding Homo_sapiens

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