C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nitric oxide synthase 1 (neuronal)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSDART00000099822 nos1-001 ENSDARG00000068910 7955 - 5:13188827-13313998 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000099822
Transcript ID Brain Heart Kidney Muscle
ENSDART00000099822 3.560±3.34 0.982±0.38 0.433±0.00 0.228±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QM CIL_0001QM_0001 CGP 5:13188827-13501138

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IEA nitric-oxide synthase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005622 IMP intracellular
GO:0005829 IBA cytosol
GO:0006809 IEA nitric oxide biosynthetic process
GO:0007263 IMP nitric oxide mediated signal transduction
GO:0010181 IEA FMN binding
GO:0016491 IEA oxidoreductase activity
GO:0020037 IEA heme binding
GO:0021517 IMP ventral spinal cord development
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0045776 IBA negative regulation of blood pressure
GO:0045909 IBA positive regulation of vasodilation
GO:0046872 IEA metal ion binding
GO:0048668 IMP collateral sprouting
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process
GO:0060218 IMP hematopoietic stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000317775 NOS1-001 protein_coding Homo_sapiens 0 1580
ENST00000338101 NOS1-002 protein_coding Homo_sapiens 0 669
ENST00000344089 NOS1-201 protein_coding Homo_sapiens 0 1580
ENST00000618760 NOS1-202 protein_coding Homo_sapiens 0 669

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