C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000075793 prex1 7955 - 8:26277004-26422863 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000078022 prex1-201 26278848-26418837 protein_coding
  ENSDART00000136869 prex1-002 26367084-26422863 protein_coding
  ENSDART00000138289 prex1-001 26277004-26419290 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000078022ENSDART00000138289
Transcript ID Brain Heart Kidney Liver
ENSDART00000078022 1.783±0.00 1.197±0.00 1.833±0.00 0.217±0.00
ENSDART00000138289 0.831±0.00 N/A 4.681±2.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0038092 IMP nodal signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000124126 PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 protein_coding Homo_sapiens
ENSMUSG00000039621 Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 protein_coding Mus_musculus

Loading