C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement factor H
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000000971 CFH 9606 + 1:196651878-196747504 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359637 CFH-002 196652056-196701565 protein_coding
  ENST00000367429 CFH-001 196651878-196747504 protein_coding
  ENST00000466229 CFH-004 196676988-196747504 retained_intron
  ENST00000470918 CFH-005 196736908-196741086 retained_intron
  ENST00000496761 CFH-003 196652056-196673407 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359637ENST00000367429ENST00000466229
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359637 9.752±0.00 13.465±0.00 N/A N/A 16.266±0.00 14.424±0.00 5.637±0.00 N/A N/A 15.928±0.00 2.136±0.00 26.550±3.76 3.726±0.00 15.304±0.00
ENST00000367429 14.962±0.00 18.053±0.00 1.717±0.00 2.725±1.20 17.084±0.91 11.486±6.49 6.578±4.45 135.198±124.29 108.702±93.99 14.523±3.05 1.632±0.40 30.474±23.05 7.115±1.98 10.343±6.06
ENST00000466229 N/A N/A N/A N/A 1.692±0.00 0.817±0.00 0.478±0.00 N/A 2.128±0.00 1.907±0.00 N/A 2.324±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001M0 CIL_0001M0_0003 CGP 1:196651878-196795406

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005615 TAS extracellular space
GO:0006956 TAS complement activation
GO:0006957 IEA complement activation, alternative pathway
GO:0008201 IDA heparin binding
GO:0030449 TAS regulation of complement activation
GO:0043395 IDA heparan sulfate proteoglycan binding
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091868 f13b coagulation factor XIII, B polypeptide protein_coding Danio_rerio
ENSDARG00000092786 cfhl5 complement factor H like 5 protein_coding Danio_rerio
ENSDARG00000094496 cfhl4 complement factor H like 4 protein_coding Danio_rerio
ENSMUSG00000026365 Cfh complement component factor h protein_coding Mus_musculus
ENSMUSG00000033898 Cfhr2 complement factor H-related 2 protein_coding Mus_musculus
ENSMUSG00000057037 Cfhr1 complement factor H-related 1 protein_coding Mus_musculus
ENSMUSG00000070594 Gm4788 predicted gene 4788 protein_coding Mus_musculus

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