C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000003989 SLC7A2 9606 + 8:17497088-17570573 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000004531 SLC7A2-201 17538777-17570561 protein_coding
  ENST00000398090 SLC7A2-202 17538777-17570561 protein_coding
  ENST00000470360 SLC7A2-002 17497215-17570573 protein_coding
  ENST00000494857 SLC7A2-001 17497088-17570573 protein_coding
  ENST00000522656 SLC7A2-003 17497091-17565274 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000004531ENST00000398090ENST00000494857ENST00000522656
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000004531 N/A 0.852±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 2.979±1.06 1.328±0.00 N/A
ENST00000398090 1.415±0.00 N/A N/A 0.921±0.00 N/A N/A 21.195±19.75 17.674±0.00 N/A 12.606±0.00 N/A N/A 1.559±0.00
ENST00000494857 1.485±0.00 0.749±0.00 4.102±2.11 1.804±0.00 4.083±3.51 1.609±0.00 11.115±6.22 3.584±1.44 3.851±2.18 N/A 9.943±0.09 1.892±0.72 6.898±4.78
ENST00000522656 N/A 1.601±0.00 N/A 2.203±0.00 N/A N/A N/A N/A 2.876±0.00 N/A 9.416±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001TT CIL_0001TT_0001 CGP 8:17497088-17644071

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000064 IEA L-ornithine transmembrane transporter activity
GO:0002537 IEA nitric oxide production involved in inflammatory response
GO:0003333 IEA amino acid transmembrane transport
GO:0005289 IEA high-affinity arginine transmembrane transporter activity
GO:0005292 IEA high-affinity lysine transmembrane transporter activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006520 TAS cellular amino acid metabolic process
GO:0006809 IEA nitric oxide biosynthetic process
GO:0006810 TAS:IEA transport
GO:0006811 TAS ion transport
GO:0006865 TAS:IEA amino acid transport
GO:0015171 IEA amino acid transmembrane transporter activity
GO:0015174 TAS basic amino acid transmembrane transporter activity
GO:0015181 IEA arginine transmembrane transporter activity
GO:0015189 IEA L-lysine transmembrane transporter activity
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0042116 IEA macrophage activation
GO:0043030 IEA regulation of macrophage activation
GO:0050727 IEA regulation of inflammatory response
GO:0055085 TAS:IEA transmembrane transport
GO:0061459 IEA L-arginine transmembrane transporter activity
GO:0097626 IEA low-affinity L-arginine transmembrane transporter activity
GO:0097627 IEA high-affinity L-ornithine transmembrane transporter activity
GO:0097638 IEA L-arginine import across plasma membrane
GO:0097639 IEA L-lysine import across plasma membrane
GO:0097640 IEA L-ornithine import across plasma membrane
GO:1902023 IEA L-arginine transport
GO:1903352 IEA L-ornithine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037097 slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 protein_coding Danio_rerio
ENSMUSG00000031596 Slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 protein_coding Mus_musculus

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