C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000004531 SLC7A2-201 ENSG00000003989 9606 + 8:17538777-17570561 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderOvaryPlacentaENST00000004531
Transcript ID Bladder Ovary Placenta
ENST00000004531 0.852±0.00 2.979±1.06 1.328±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001TT CIL_0001TT_0001 CGP 8:17497088-17644071

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000064 IEA L-ornithine transmembrane transporter activity
GO:0002537 IEA nitric oxide production involved in inflammatory response
GO:0005289 IEA high-affinity arginine transmembrane transporter activity
GO:0005292 IEA high-affinity lysine transmembrane transporter activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006520 TAS cellular amino acid metabolic process
GO:0006809 IEA nitric oxide biosynthetic process
GO:0006810 TAS:IEA transport
GO:0006811 TAS ion transport
GO:0006865 TAS:IEA amino acid transport
GO:0015174 TAS basic amino acid transmembrane transporter activity
GO:0015181 IEA arginine transmembrane transporter activity
GO:0015189 IEA L-lysine transmembrane transporter activity
GO:0016020 TAS:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0042116 IEA macrophage activation
GO:0043030 IEA regulation of macrophage activation
GO:0050727 IEA regulation of inflammatory response
GO:0055085 TAS:IEA transmembrane transport
GO:0061459 IEA L-arginine transmembrane transporter activity
GO:0097626 IEA low-affinity L-arginine transmembrane transporter activity
GO:0097627 IEA high-affinity L-ornithine transmembrane transporter activity
GO:0097638 IEA L-arginine import across plasma membrane
GO:0097639 IEA L-lysine import across plasma membrane
GO:0097640 IEA L-ornithine import across plasma membrane
GO:1902023 IEA L-arginine transport
GO:1903352 IEA L-ornithine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117077 Slc7a2-002 protein_coding Mus_musculus 0 2158
ENSMUST00000098816 Slc7a2-003 protein_coding Mus_musculus 0 2158
ENSMUST00000118432 Slc7a2-004 protein_coding Mus_musculus 0 1860
ENSMUST00000057784 Slc7a2-001 protein_coding Mus_musculus 0 1860

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