C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031596 Slc7a2 10090 + 8:40862396-40922308 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000057784 Slc7a2-001 40862412-40922308 protein_coding
  ENSMUST00000098816 Slc7a2-003 40862396-40918056 protein_coding
  ENSMUST00000117077 Slc7a2-002 40874948-40922070 protein_coding
  ENSMUST00000118432 Slc7a2-004 40898438-40917726 protein_coding
  ENSMUST00000141505 Slc7a2-005 40862578-40898982 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000057784ENSMUST00000098816ENSMUST00000117077ENSMUST00000118432ENSMUST00000141505
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000057784 0.781±0.00 2.607±0.74 N/A N/A 8.368±2.46 0.200±0.09 0.292±0.22 0.657±0.20 27.716±23.68 1.592±0.57 6.604±2.62 2.796±0.00 2.277±2.79 0.258±0.08
ENSMUST00000098816 2.893±1.72 9.627±2.02 N/A 0.198±0.00 6.646±1.31 0.341±0.18 0.410±0.08 0.918±0.16 15.708±6.44 5.781±1.13 N/A 3.971±1.31 0.943±0.37 0.658±0.08
ENSMUST00000117077 N/A N/A 0.514±0.33 0.999±0.00 2.440±0.00 0.103±0.00 N/A N/A N/A N/A 1.609±0.09 2.985±0.40 1.545±1.33 0.195±0.04
ENSMUST00000118432 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.227±0.00
ENSMUST00000141505 N/A N/A N/A N/A N/A 0.460±0.09 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001TT CIL_0001TT_0002 CGP 8:40862396-40990785

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000064 IDA L-ornithine transmembrane transporter activity
GO:0002537 IMP nitric oxide production involved in inflammatory response
GO:0005289 IDA high-affinity arginine transmembrane transporter activity
GO:0005292 IDA high-affinity lysine transmembrane transporter activity
GO:0006809 IMP nitric oxide biosynthetic process
GO:0015181 IMP arginine transmembrane transporter activity
GO:0015189 IDA L-lysine transmembrane transporter activity
GO:0016021 IDA integral component of membrane
GO:0042116 IMP macrophage activation
GO:0043030 IMP regulation of macrophage activation
GO:0050727 IMP regulation of inflammatory response
GO:0061459 IMP L-arginine transmembrane transporter activity
GO:0097626 IDA low-affinity L-arginine transmembrane transporter activity
GO:0097627 IDA high-affinity L-ornithine transmembrane transporter activity
GO:0097638 IDA L-arginine import across plasma membrane
GO:0097639 IDA L-lysine import across plasma membrane
GO:0097640 IDA L-ornithine import across plasma membrane
GO:1902023 IMP L-arginine transport
GO:1903352 IDA L-ornithine transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037097 slc7a2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 protein_coding Danio_rerio
ENSG00000003989 SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 protein_coding Homo_sapiens

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