C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family B (MDR/TAP), member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000004846 ABCB5 9606 + 7:20615207-20777038 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000258738 ABCB5-001 20647422-20755624 protein_coding
  ENST00000404938 ABCB5-004 20615207-20757009 protein_coding
  ENST00000406935 ABCB5-002 20647343-20667323 protein_coding
  ENST00000441315 ABCB5-007 20723094-20777038 nonsense_mediated_decay
  ENST00000443026 ABCB5-003 20647343-20660394 protein_coding
  ENST00000477094 ABCB5-006 20647330-20651696 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000258738ENST00000404938ENST00000406935ENST00000441315ENST00000443026ENST00000477094
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000258738 0.287±0.00 N/A N/A N/A N/A 0.124±0.04 N/A N/A N/A N/A N/A N/A 0.026±0.00 0.094±0.00
ENST00000404938 N/A 0.031±0.00 N/A 0.017±0.00 0.081±0.00 N/A 0.011±0.00 0.008±0.00 0.083±0.00 N/A N/A 0.024±0.02 0.009±0.00 0.085±0.05
ENST00000406935 N/A N/A N/A N/A 0.140±0.00 N/A 0.014±0.00 N/A N/A N/A 0.058±0.00 N/A N/A N/A
ENST00000441315 N/A N/A N/A N/A N/A N/A 0.116±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000443026 N/A 0.042±0.00 0.328±0.00 0.014±0.00 N/A 0.085±0.00 0.038±0.00 0.077±0.00 0.016±0.00 0.020±0.00 0.054±0.00 0.048±0.00 N/A N/A
ENST00000477094 N/A N/A 0.491±0.00 N/A N/A N/A N/A N/A 1.909±0.00 0.105±0.00 N/A 0.038±0.01 0.030±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UH CIL_0007UH_0001 VISTA 7:20489771-21090788
CIL_0007YM CIL_0007YM_0001 VISTA 7:20493009-21094283
CIL_0007Z1 CIL_0007Z1_0001 VISTA 7:20499224-21100776

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002481 IBA antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 IBA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 IBA antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 IBA positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0015562 IDA efflux transmembrane transporter activity
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0030154 IEA cell differentiation
GO:0042391 IDA regulation of membrane potential
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0048058 ISS compound eye corneal lens development
GO:0055085 IDA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000072791 Abcb5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 protein_coding Mus_musculus

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