C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aminolevulinate, delta-, synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000023330 ALAS1 9606 + 3:52198086-52214327 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310271 ALAS1-003 52198132-52214324 protein_coding
  ENST00000394965 ALAS1-001 52198094-52214327 protein_coding
  ENST00000459884 ALAS1-006 52211452-52212507 protein_coding
  ENST00000469224 ALAS1-002 52198086-52214180 protein_coding
  ENST00000484952 ALAS1-004 52198144-52214292 protein_coding
  ENST00000493402 ALAS1-007 52206632-52214225 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310271ENST00000394965ENST00000469224ENST00000484952ENST00000493402
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310271 7.658±0.00 6.362±0.00 N/A 12.483±0.00 9.002±0.00 5.672±0.00 17.146±0.00 12.645±0.00 47.619±0.00 5.243±2.45 6.208±0.00 11.578±6.86 12.971±1.84 11.058±0.00
ENST00000394965 N/A N/A N/A N/A N/A N/A 1.091±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000469224 10.332±0.00 7.235±0.00 1.357±0.00 7.665±1.62 6.846±4.10 4.292±0.75 15.076±8.36 21.554±4.87 22.239±19.07 10.552±4.35 9.834±2.19 9.573±7.78 12.762±5.35 10.051±2.67
ENST00000484952 2.505±0.00 N/A N/A 4.247±0.00 2.169±1.29 1.522±0.31 3.900±2.85 4.367±0.00 15.560±13.90 8.040±0.00 3.129±0.00 N/A 4.021±0.74 2.343±0.00
ENST00000493402 N/A 7.657±0.00 N/A N/A N/A N/A N/A N/A 52.560±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087C CIL_00087C_0001 VISTA 3:51705330-52307529
CIL_0008NT CIL_0008NT_0001 VISTA 3:51738719-52342071
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003870 IEA 5-aminolevulinate synthase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005759 TAS:IEA mitochondrial matrix
GO:0006778 TAS:IEA porphyrin-containing compound metabolic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 TAS heme biosynthetic process
GO:0008152 IEA metabolic process
GO:0009058 IEA biosynthetic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0033014 IEA tetrapyrrole biosynthetic process
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021059 alas1 aminolevulinate, delta-, synthetase 1 protein_coding Danio_rerio
ENSMUSG00000032786 Alas1 aminolevulinic acid synthase 1 protein_coding Mus_musculus

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