C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, eta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000027075 PRKCH 9606 + 14:61187559-61550976 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332981 PRKCH-001 61321717-61550976 protein_coding
  ENST00000536400 PRKCH-003 61477167-61549946 processed_transcript
  ENST00000552875 PRKCH-018 61322753-61353989 processed_transcript
  ENST00000553265 PRKCH-021 61347891-61450885 protein_coding
  ENST00000553726 PRKCH-020 61344324-61457181 protein_coding
  ENST00000553830 PRKCH-017 61326913-61445721 protein_coding
  ENST00000553831 PRKCH-019 61344242-61450872 protein_coding
  ENST00000553846 PRKCH-024 61527937-61547846 processed_transcript
  ENST00000553889 PRKCH-007 61452771-61457653 processed_transcript
  ENST00000554835 PRKCH-016 61281184-61299854 processed_transcript
  ENST00000555082 PRKCH-002 61322664-61550976 protein_coding
  ENST00000555110 PRKCH-026 61525090-61529205 processed_transcript
  ENST00000555185 PRKCH-014 61187559-61530584 protein_coding
  ENST00000555233 PRKCH-009 61463069-61529209 processed_transcript
  ENST00000555382 PRKCH-010 61525652-61547886 processed_transcript
  ENST00000555542 PRKCH-015 61280953-61443211 protein_coding
  ENST00000555604 PRKCH-013 61457506-61476516 processed_transcript
  ENST00000555628 PRKCH-025 61492193-61547864 processed_transcript
  ENST00000555906 PRKCH-023 61281149-61449252 protein_coding
  ENST00000556164 PRKCH-022 61361074-61449247 protein_coding
  ENST00000556245 PRKCH-004 61543362-61550972 processed_transcript
  ENST00000556778 PRKCH-028 61187569-61453265 protein_coding
  ENST00000557294 PRKCH-027 61187569-61322455 protein_coding
  ENST00000557473 PRKCH-006 61442558-61450941 protein_coding
  ENST00000557559 PRKCH-008 61456842-61457625 processed_transcript
  ENST00000557585 PRKCH-005 61390694-61457557 protein_coding
  ENST00000557599 PRKCH-011 61525652-61549802 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332981ENST00000536400ENST00000553889ENST00000555082ENST00000556245ENST00000556778ENST00000557473ENST00000557585
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332981 13.637±0.00 12.170±0.00 0.786±0.00 2.062±0.00 3.901±1.03 4.435±2.83 3.015±1.91 4.847±0.00 2.148±0.50 15.504±13.37 5.266±0.00 3.566±1.00 10.143±3.33 3.568±0.00
ENST00000536400 N/A N/A N/A N/A N/A N/A 4.691±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000553889 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.671±0.00 N/A N/A N/A
ENST00000555082 5.536±0.00 N/A N/A 0.784±0.00 3.158±0.00 N/A 1.653±0.00 N/A 1.186±0.00 6.466±0.00 3.933±0.00 1.357±0.00 5.238±2.18 3.429±0.80
ENST00000556245 N/A N/A N/A N/A N/A N/A N/A 1.068±0.00 N/A N/A N/A N/A N/A N/A
ENST00000556778 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.333±0.00 N/A N/A N/A
ENST00000557473 N/A N/A 4.146±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000557585 N/A N/A N/A 2.142±0.00 7.166±0.00 N/A N/A N/A N/A 12.280±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SI CIL_0006SI_0002 CGP 14:60981114-61550976

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004697 TAS:IEA protein kinase C activity
GO:0004699 IEA calcium-independent protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0006468 IMP:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0017160 IEA Ral GTPase binding
GO:0019899 IPI enzyme binding
GO:0030168 TAS platelet activation
GO:0034351 IMP negative regulation of glial cell apoptotic process
GO:0035556 IEA intracellular signal transduction
GO:0045618 ISS positive regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0050861 IMP positive regulation of B cell receptor signaling pathway
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0060252 IMP positive regulation of glial cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:0070528 IEA protein kinase C signaling
GO:2000810 IMP regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018382 prkcha protein kinase C, eta, a protein_coding Danio_rerio
ENSDARG00000043243 prkchb protein kinase C, eta, b protein_coding Danio_rerio
ENSMUSG00000021108 Prkch protein kinase C, eta protein_coding Mus_musculus

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