C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase C, eta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021108 Prkch 10090 + 12:73584797-73778185 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021527 Prkch-001 73584797-73778185 protein_coding
  ENSMUST00000119092 Prkch-002 73584843-73761542 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021527ENSMUST00000119092
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021527 7.273±1.10 1.853±0.39 7.219±2.38 2.276±0.24 8.937±1.81 2.721±0.53 4.875±0.25 4.662±0.22 0.993±0.44 24.467±1.31 2.072±0.36 3.217±0.89 15.356±5.44 0.411±0.16
ENSMUST00000119092 N/A 0.611±0.17 N/A 0.386±0.00 1.231±0.00 N/A N/A N/A 0.090±0.00 N/A N/A 0.646±0.13 N/A 0.162±0.12

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00006H CIL_00006H_0002 CGP 12:73584797-73947530

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004697 IEA protein kinase C activity
GO:0004699 IEA calcium-independent protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006468 ISS protein phosphorylation
GO:0010744 IMP positive regulation of macrophage derived foam cell differentiation
GO:0016020 IEA membrane
GO:0017160 IPI Ral GTPase binding
GO:0019899 IEA enzyme binding
GO:0034351 ISS negative regulation of glial cell apoptotic process
GO:0035556 IEA intracellular signal transduction
GO:0045618 IMP positive regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0050861 ISS positive regulation of B cell receptor signaling pathway
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060252 ISS positive regulation of glial cell proliferation
GO:0070062 IEA extracellular vesicular exosome
GO:0070528 IEA protein kinase C signaling
GO:2000810 ISS regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018382 prkcha protein kinase C, eta, a protein_coding Danio_rerio
ENSDARG00000043243 prkchb protein kinase C, eta, b protein_coding Danio_rerio
ENSG00000027075 PRKCH protein kinase C, eta protein_coding Homo_sapiens

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