C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase C, eta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000555082 PRKCH-002 ENSG00000027075 9606 + 14:61322664-61550976 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartLiverLungMuscleOvaryPlacentaTestisENST00000555082
Transcript ID Adipose Brain Breast Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000555082 5.536±0.00 0.784±0.00 3.158±0.00 1.653±0.00 1.186±0.00 6.466±0.00 3.933±0.00 1.357±0.00 5.238±2.18 3.429±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006SI CIL_0006SI_0002 CGP 14:60981114-61550976

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004697 TAS protein kinase C activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IMP:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007596 TAS blood coagulation
GO:0010744 ISS positive regulation of macrophage derived foam cell differentiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019899 IPI enzyme binding
GO:0030168 TAS platelet activation
GO:0034351 IMP negative regulation of glial cell apoptotic process
GO:0035556 IEA intracellular signal transduction
GO:0045618 ISS positive regulation of keratinocyte differentiation
GO:0046872 IEA metal ion binding
GO:0050861 IMP positive regulation of B cell receptor signaling pathway
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0060252 IMP positive regulation of glial cell proliferation
GO:0070062 IDA extracellular vesicular exosome
GO:2000810 IMP regulation of tight junction assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021527 Prkch-001 protein_coding Mus_musculus 0 2180
ENSMUST00000119092 Prkch-002 protein_coding Mus_musculus 0 1746
ENSMUST00000059595 Prkca-001 protein_coding Mus_musculus 2e-23 115
ENSMUST00000134910 Prkca-003 processed_transcript Mus_musculus 3e-17 95

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