C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: poly (ADP-ribose) polymerase family, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000041880 PARP3 9606 + 3:51942345-51948867 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000398755 PARP3-001 51942359-51948862 protein_coding
  ENST00000417220 PARP3-002 51942345-51948862 protein_coding
  ENST00000431474 PARP3-201 51942345-51948867 protein_coding
  ENST00000470601 PARP3-007 51942937-51944900 retained_intron
  ENST00000470749 PARP3-004 51943299-51944717 retained_intron
  ENST00000471971 PARP3-003 51942371-51948603 nonsense_mediated_decay
  ENST00000475782 PARP3-006 51944787-51946261 retained_intron
  ENST00000486510 PARP3-008 51947625-51948482 processed_transcript
  ENST00000498510 PARP3-005 51943311-51945628 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000398755ENST00000417220ENST00000431474ENST00000470601ENST00000470749ENST00000471971ENST00000486510ENST00000498510
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000398755 2.424±0.00 N/A 1.099±0.00 2.323±0.64 3.240±2.58 0.801±0.00 1.252±1.11 N/A 1.619±0.00 1.885±1.56 0.832±0.00 2.184±1.46 0.620±0.00 2.936±0.89
ENST00000417220 N/A N/A N/A N/A N/A N/A 0.649±0.00 1.376±0.00 N/A 0.413±0.00 N/A 0.971±0.00 0.680±0.00 0.924±0.00
ENST00000431474 1.480±0.00 N/A N/A N/A 0.974±0.00 N/A N/A N/A 0.502±0.00 4.117±0.00 N/A 2.234±1.26 1.318±0.00 1.260±0.00
ENST00000470601 N/A N/A N/A 0.557±0.00 N/A N/A 0.365±0.00 N/A N/A N/A N/A 2.542±0.00 N/A 3.538±0.00
ENST00000470749 N/A N/A 3.108±0.00 N/A N/A 0.928±0.00 N/A 2.884±0.00 1.247±0.00 N/A N/A 0.374±0.00 N/A N/A
ENST00000471971 N/A N/A N/A N/A N/A 0.833±0.39 N/A N/A N/A N/A 0.413±0.00 N/A N/A N/A
ENST00000486510 N/A 15.110±0.00 N/A N/A 20.355±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000498510 N/A N/A N/A N/A 7.096±0.00 1.050±0.00 0.298±0.00 N/A N/A 0.900±0.00 1.858±0.00 3.652±0.00 4.213±0.00 3.119±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087C CIL_00087C_0001 VISTA 3:51705330-52307529
CIL_0008NT CIL_0008NT_0001 VISTA 3:51738719-52342071

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IMP telomere maintenance
GO:0003824 TAS catalytic activity
GO:0003950 IDA:IEA NAD+ ADP-ribosyltransferase activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006281 TAS DNA repair
GO:0006302 IMP double-strand break repair
GO:0006471 IDA:IEA protein ADP-ribosylation
GO:0035861 IDA site of double-strand break
GO:0051106 IGI positive regulation of DNA ligation
GO:0060236 IMP regulation of mitotic spindle organization
GO:1990166 IMP protein localization to site of double-strand break

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003961 parp3 poly (ADP-ribose) polymerase family, member 3 protein_coding Danio_rerio
ENSMUSG00000023249 Parp3 poly (ADP-ribose) polymerase family, member 3 protein_coding Mus_musculus

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