C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: translocated promoter region, nuclear basket protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000047410 TPR 9606 - 1:186311652-186375693 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367478 TPR-001 186311652-186375325 protein_coding
  ENST00000451586 TPR-003 186373393-186375693 protein_coding
  ENST00000467810 TPR-008 186318505-186322701 processed_transcript
  ENST00000469463 TPR-005 186351952-186353948 retained_intron
  ENST00000474852 TPR-002 186352015-186375325 processed_transcript
  ENST00000481347 TPR-006 186338187-186344090 retained_intron
  ENST00000491783 TPR-004 186351423-186356538 retained_intron
  ENST00000492973 TPR-007 186325519-186326220 retained_intron
  ENST00000613151 TPR-201 186353871-186375325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367478ENST00000613151
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367478 5.402±0.00 3.619±0.00 0.680±0.00 3.371±1.82 3.088±0.61 4.865±2.69 1.542±0.00 4.448±2.21 4.024±0.00 1.395±0.00 3.436±2.80 7.255±3.86 4.964±2.07 17.624±10.91
ENST00000613151 N/A N/A 1.991±0.00 N/A 8.255±0.00 N/A 1.972±0.00 N/A 5.138±0.00 7.819±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001BO CIL_0001BO_0003 CGP 1:186296279-186375693
CIL_0001BN CIL_0001BN_0002 CGP 1:186311652-186421378

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000166 IEA nucleotide binding
GO:0000189 IMP MAPK import into nucleus
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0003682 IDA chromatin binding
GO:0003729 IDA mRNA binding
GO:0005487 IDA nucleocytoplasmic transporter activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005643 IDA:IEA nuclear pore
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005868 IDA cytoplasmic dynein complex
GO:0005975 TAS carbohydrate metabolic process
GO:0006404 IDA RNA import into nucleus
GO:0006405 IMP RNA export from nucleus
GO:0006606 IEA protein import into nucleus
GO:0006999 IMP nuclear pore organization
GO:0007067 IEA mitotic nuclear division
GO:0007077 TAS mitotic nuclear envelope disassembly
GO:0007094 IMP mitotic spindle assembly checkpoint
GO:0008645 TAS hexose transport
GO:0010827 TAS regulation of glucose transport
GO:0010965 IMP regulation of mitotic sister chromatid separation
GO:0015631 IDA tubulin binding
GO:0015758 TAS glucose transport
GO:0016032 TAS viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0019898 IDA extrinsic component of membrane
GO:0031072 IDA heat shock protein binding
GO:0031453 IMP positive regulation of heterochromatin assembly
GO:0031965 IDA nuclear membrane
GO:0031990 IDA mRNA export from nucleus in response to heat stress
GO:0034399 IDA nuclear periphery
GO:0034605 IDA cellular response to heat
GO:0035457 ISS cellular response to interferon-alpha
GO:0042307 IMP positive regulation of protein import into nucleus
GO:0042405 IDA nuclear inclusion body
GO:0042803 IDA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0044615 IDA nuclear pore nuclear basket
GO:0044822 IDA poly(A) RNA binding
GO:0045947 IMP negative regulation of translational initiation
GO:0046827 ISS positive regulation of protein export from nucleus
GO:0046832 IMP negative regulation of RNA export from nucleus
GO:0051019 IDA mitogen-activated protein kinase binding
GO:0055085 TAS transmembrane transport
GO:0070840 IDA dynein complex binding
GO:0070849 IDA response to epidermal growth factor
GO:0072686 IDA mitotic spindle
GO:0090267 IMP positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090316 IMP positive regulation of intracellular protein transport
GO:1901673 IMP regulation of spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016630 tprb translocated promoter region b (to activated MET oncogene) protein_coding Danio_rerio
ENSDARG00000052914 tpra translocated promoter region a (to activated MET oncogene) protein_coding Danio_rerio
ENSMUSG00000006005 Tpr translocated promoter region, nuclear basket protein protein_coding Mus_musculus

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