C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: translocated promoter region, nuclear basket protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006005 Tpr 10090 + 1:150392838-150449935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000119161 Tpr-001 150393250-150449935 protein_coding
  ENSMUST00000124484 Tpr-012 150445918-150449927 protein_coding
  ENSMUST00000124973 Tpr-002 150392838-150449815 protein_coding
  ENSMUST00000128417 Tpr-006 150440197-150449927 retained_intron
  ENSMUST00000130779 Tpr-013 150448871-150449791 processed_transcript
  ENSMUST00000131701 Tpr-007 150393384-150395495 retained_intron
  ENSMUST00000132257 Tpr-011 150437435-150443222 retained_intron
  ENSMUST00000132522 Tpr-009 150424739-150428353 retained_intron
  ENSMUST00000138718 Tpr-014 150447455-150449929 retained_intron
  ENSMUST00000141827 Tpr-010 150411997-150413963 retained_intron
  ENSMUST00000147769 Tpr-008 150414788-150416403 retained_intron
  ENSMUST00000150752 Tpr-004 150430424-150440312 retained_intron
  ENSMUST00000151563 Tpr-003 150429364-150440315 protein_coding
  ENSMUST00000152967 Tpr-005 150438932-150449927 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000119161ENSMUST00000124973ENSMUST00000128417ENSMUST00000150752ENSMUST00000151563
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000119161 4.053±0.30 15.469±5.41 2.539±0.00 4.349±1.44 12.816±5.35 5.941±1.25 2.006±0.17 2.818±0.43 3.265±1.18 9.654±4.12 N/A 8.627±5.54 4.085±1.20 1.244±0.07
ENSMUST00000124973 2.929±0.55 3.553±0.00 5.164±1.25 11.913±10.50 3.696±0.42 1.883±0.07 3.658±0.97 1.692±0.24 5.056±2.82 3.100±0.14 5.936±0.67 14.436±14.74 23.271±17.50 6.329±4.67
ENSMUST00000128417 N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.849±0.00 N/A N/A N/A N/A
ENSMUST00000150752 17.198±0.00 N/A N/A N/A N/A 7.388±0.00 11.657±0.00 9.635±1.06 N/A 13.677±2.28 N/A 13.281±2.88 N/A N/A
ENSMUST00000151563 N/A N/A 15.839±2.50 33.256±14.99 11.415±0.00 N/A 7.475±0.00 8.757±0.00 14.068±7.28 N/A 10.335±0.78 30.457±28.04 49.716±39.13 22.264±24.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000189 ISS MAPK import into nucleus
GO:0000776 ISS kinetochore
GO:0003682 ISS chromatin binding
GO:0003729 ISS mRNA binding
GO:0005487 ISS nucleocytoplasmic transporter activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005635 IDA nuclear envelope
GO:0005643 ISS nuclear pore
GO:0005737 ISS cytoplasm
GO:0005868 ISS cytoplasmic dynein complex
GO:0006404 ISS RNA import into nucleus
GO:0006405 ISS RNA export from nucleus
GO:0006999 ISS nuclear pore organization
GO:0007067 IEA mitotic nuclear division
GO:0007094 ISS mitotic spindle assembly checkpoint
GO:0010965 ISS regulation of mitotic sister chromatid separation
GO:0015631 IEA tubulin binding
GO:0019898 ISS extrinsic component of membrane
GO:0031072 ISS heat shock protein binding
GO:0031453 ISS positive regulation of heterochromatin assembly
GO:0031965 ISS nuclear membrane
GO:0031990 ISS mRNA export from nucleus in response to heat stress
GO:0034399 ISS nuclear periphery
GO:0034605 ISS cellular response to heat
GO:0035457 IDA cellular response to interferon-alpha
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0042405 ISS nuclear inclusion body
GO:0042803 ISS protein homodimerization activity
GO:0044615 ISS nuclear pore nuclear basket
GO:0044822 IEA poly(A) RNA binding
GO:0045947 ISS negative regulation of translational initiation
GO:0046827 ISS positive regulation of protein export from nucleus
GO:0046832 ISS negative regulation of RNA export from nucleus
GO:0051019 ISS mitogen-activated protein kinase binding
GO:0070840 IEA dynein complex binding
GO:0070849 ISS response to epidermal growth factor
GO:0072686 ISS mitotic spindle
GO:0090267 ISS positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090316 ISS positive regulation of intracellular protein transport
GO:1901673 ISS regulation of spindle assembly involved in mitosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016630 tprb translocated promoter region b (to activated MET oncogene) protein_coding Danio_rerio
ENSDARG00000052914 tpra translocated promoter region a (to activated MET oncogene) protein_coding Danio_rerio
ENSG00000047410 TPR translocated promoter region, nuclear basket protein protein_coding Homo_sapiens

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